抗代谢物(微)

Objective: To explore the effect of promoting filtration bleb with antimetabolites in rabbits. 目的：探讨兔眼滤过手术中抗代谢药物促滤泡形成的作用。

Antimetabolites,interferins and heperin were used experimentally and clinically for glaucoma filtering surgery. 如：抗代谢药物、干扰素、肝素等已用于滤过术后的实验及临床研究。

Abstract：In the anti-cancer drugs, there is a category of Antimetabolites drugs containing pyrimidine-tract structure such as Funimiding and Azacytidine. 摘要：在抗癌药物中有一类抗代谢药物含有嘧啶环结构，如氟尿嘧啶、氮杂胞苷等。

In vitro screening in tissue culture provides the capacity to isolate biochemical mutants, particularly those which confer resistance to antimetabolites. 组织培养体外筛选提供分离生化突变体的能力，特别是那些对抗代谢产物产生抗性的突变体。

Keywords glaucoma;rabbit;filtering surgery;antimetabolites;laser; 青光眼;滤过手术;抗代谢药物;激光;